{"id":2853944,"date":"2026-10-05T10:47:04","date_gmt":"2026-10-05T07:47:04","guid":{"rendered":"https:\/\/eportal.gr\/portal\/?p=2853944"},"modified":"2026-10-05T10:47:04","modified_gmt":"2026-10-05T07:47:04","slug":"%ce%bd%ce%b5%cf%8c%cf%84%ce%b5%cf%81%ce%b5%cf%82-%ce%b5%ce%be%ce%b5%ce%bb%ce%af%ce%be%ce%b5%ce%b9%cf%82-%cf%83%cf%84%ce%b7-%ce%b8%ce%b5%cf%81%ce%b1%cf%80%ce%b5%ce%af%ce%b1-%cf%84%ce%bf%cf%85-%cf%80","status":"publish","type":"post","link":"https:\/\/eportal.gr\/portal\/%ce%bd%ce%b5%cf%8c%cf%84%ce%b5%cf%81%ce%b5%cf%82-%ce%b5%ce%be%ce%b5%ce%bb%ce%af%ce%be%ce%b5%ce%b9%cf%82-%cf%83%cf%84%ce%b7-%ce%b8%ce%b5%cf%81%ce%b1%cf%80%ce%b5%ce%af%ce%b1-%cf%84%ce%bf%cf%85-%cf%80\/","title":{"rendered":"\u039d\u03b5\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03b5\u03be\u03b5\u03bb\u03af\u03be\u03b5\u03b9\u03c2 \u03c3\u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c4\u03bf\u03c5 \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03bf\u03cd \u03bc\u03c5\u03b5\u03bb\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2"},"content":{"rendered":"<p> \n<\/p>\n<div>\n<p><span style=\"font-weight: 400;\">\u03a3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03bb\u03af\u03be\u03b5\u03b9\u03c2 \u03c3\u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c4\u03bf\u03c5 \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03bf\u03cd \u03bc\u03c5\u03b5\u03bb\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03b9\u03ac\u03c3\u03c4\u03b7\u03ba\u03b1\u03bd \u03c3\u03c4\u03bf 23\u03bf \u0395\u03c4\u03ae\u03c3\u03b9\u03bf \u03a3\u03c5\u03bd\u03ad\u03b4\u03c1\u03b9\u03bf \u03c4\u03b7\u03c2 International Myeloma Society (IMS), \u03c0\u03bf\u03c5 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03bf\u03c0\u03bf\u03b9\u03ae\u03b8\u03b7\u03ba\u03b5 \u03c3\u03c4\u03b9\u03c2 23\u201326 \u03a3\u03b5\u03c0\u03c4\u03b5\u03bc\u03b2\u03c1\u03af\u03bf\u03c5 2026 \u03c3\u03c4\u03b7 \u0393\u03bb\u03b1\u03c3\u03ba\u03ce\u03b2\u03b7. \u03a4\u03b1 \u03bd\u03ad\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03b1\u03c6\u03bf\u03c1\u03bf\u03cd\u03bd \u03c4\u03b7 \u03bc\u03b1\u03ba\u03c1\u03bf\u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03c9\u03bd \u03c3\u03cd\u03b3\u03c7\u03c1\u03bf\u03bd\u03c9\u03bd \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ce\u03bd \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03ce\u03bd, \u03c4\u03b7\u03bd \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7 \u03c4\u03c9\u03bd CAR-T \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03b9\u03ce\u03bd \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03bd\u03ad\u03c9\u03bd \u03b1\u03bd\u03bf\u03c3\u03bf\u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ce\u03bd \u03c0\u03c1\u03bf\u03c3\u03b5\u03b3\u03b3\u03af\u03c3\u03b5\u03c9\u03bd, \u03b5\u03bd\u03ce \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b7 \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1 \u03b5\u03af\u03c7\u03b5 \u03b7 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1\u03c3\u03b7 \u03b5\u03bd\u03cc\u03c2 \u03bd\u03ad\u03bf\u03c5 \u03c0\u03bb\u03b1\u03b9\u03c3\u03af\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03c4\u03bf\u03bd \u03bf\u03c1\u03b9\u03c3\u03bc\u03cc \u03c4\u03b7\u03c2 \u03af\u03b1\u03c3\u03b7\u03c2 \u03c3\u03c4\u03bf \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03bf\u03cd\u03bd \u03bc\u03c5\u03ad\u03bb\u03c9\u03bc\u03b1.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u03a3\u03c4\u03bf \u03c6\u03b5\u03c4\u03b9\u03bd\u03cc \u03c3\u03c5\u03bd\u03ad\u03b4\u03c1\u03b9\u03bf \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03b9\u03ac\u03c3\u03c4\u03b7\u03ba\u03b1\u03bd \u03ba\u03c1\u03b9\u03c4\u03ae\u03c1\u03b9\u03b1 \u03c4\u03c9\u03bd International Myeloma Society \u03ba\u03b1\u03b9 International Myeloma Working Group (IMS\/IMWG) \u03c3\u03cd\u03bc\u03c6\u03c9\u03bd\u03b1 \u03bc\u03b5 \u03c4\u03b1 \u03bf\u03c0\u03bf\u03af\u03b1 \u03b7 \u03af\u03b1\u03c3\u03b7 \u03c0\u03c1\u03bf\u03cb\u03c0\u03bf\u03b8\u03ad\u03c4\u03b5\u03b9 \u03bf \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03bd\u03b1 \u03b2\u03c1\u03af\u03c3\u03ba\u03b5\u03c4\u03b1\u03b9 \u03b5\u03ba\u03c4\u03cc\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2, \u03bd\u03b1 \u03b4\u03b9\u03b1\u03c4\u03b7\u03c1\u03b5\u03af \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae \u03b5\u03bb\u03ac\u03c7\u03b9\u03c3\u03c4\u03b7 \u03c5\u03c0\u03bf\u03bb\u03b5\u03b9\u03c0\u03cc\u03bc\u03b5\u03bd\u03b7 \u03bd\u03cc\u03c3\u03bf (MRD) \u03b5\u03c0\u03af \u03c0\u03ad\u03bd\u03c4\u03b5 \u03ad\u03c4\u03b7 \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b1\u03c0\u03b5\u03b9\u03ba\u03bf\u03bd\u03b9\u03c3\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2. \u039f \u03bd\u03ad\u03bf\u03c2 \u03bf\u03c1\u03b9\u03c3\u03bc\u03cc\u03c2 \u03b8\u03b1 \u03c7\u03c1\u03b5\u03b9\u03b1\u03c3\u03c4\u03b5\u03af \u03bd\u03b1 \u03b5\u03c0\u03b9\u03ba\u03c5\u03c1\u03c9\u03b8\u03b5\u03af \u03bc\u03b5 \u03bc\u03b1\u03ba\u03c1\u03bf\u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1, \u03b1\u03bd\u03c4\u03b1\u03bd\u03b1\u03ba\u03bb\u03ac \u03cc\u03bc\u03c9\u03c2 \u03c4\u03b7 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03c0\u03c1\u03cc\u03bf\u03b4\u03bf \u03c0\u03bf\u03c5 \u03ad\u03c7\u03b5\u03b9 \u03b5\u03c0\u03b9\u03c4\u03b5\u03c5\u03c7\u03b8\u03b5\u03af \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03c3\u03c4\u03b1\u03b4\u03b9\u03b1\u03ba\u03ae \u03bc\u03b5\u03c4\u03b1\u03c4\u03cc\u03c0\u03b9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03bf\u03cd \u03c3\u03c4\u03cc\u03c7\u03bf\u03c5 \u03c0\u03c1\u03bf\u03c2 \u03b5\u03be\u03b1\u03b9\u03c1\u03b5\u03c4\u03b9\u03ba\u03ac \u03bc\u03b1\u03ba\u03c1\u03bf\u03c7\u03c1\u03cc\u03bd\u03b9\u03b5\u03c2 \u03c5\u03c6\u03ad\u03c3\u03b5\u03b9\u03c2 \u03c7\u03c9\u03c1\u03af\u03c2 \u03c3\u03c5\u03bd\u03b5\u03c7\u03ae \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u0399\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03bf \u03b5\u03bd\u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03bf\u03bd \u03b5\u03af\u03c7\u03b1\u03bd \u03c4\u03b1 \u03bc\u03b1\u03ba\u03c1\u03bf\u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7\u03c2 PERSEUS \u03c3\u03b5 \u03bd\u03b5\u03bf\u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03b8\u03ad\u03bd\u03c4\u03b5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bb\u03b7\u03bb\u03bf\u03c5\u03c2 \u03b3\u03b9\u03b1 \u03b1\u03c5\u03c4\u03cc\u03bb\u03bf\u03b3\u03b7 \u03bc\u03b5\u03c4\u03b1\u03bc\u03cc\u03c3\u03c7\u03b5\u03c5\u03c3\u03b7. \u039c\u03b5 \u03b4\u03b9\u03ac\u03bc\u03b5\u03c3\u03b7 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 81,3 \u03bc\u03b7\u03bd\u03ce\u03bd, \u03b7 \u03b5\u03c0\u03b9\u03b2\u03af\u03c9\u03c3\u03b7 \u03c7\u03c9\u03c1\u03af\u03c2 \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03c3\u03c4\u03bf\u03c5\u03c2 72 \u03bc\u03ae\u03bd\u03b5\u03c2 \u03ae\u03c4\u03b1\u03bd 81,1% \u03bc\u03b5 DVRd \u03ba\u03b1\u03b9 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c3\u03c5\u03bd\u03c4\u03ae\u03c1\u03b7\u03c3\u03b7\u03c2 \u03bc\u03b5 daratumumab-lenalidomide \u03ad\u03bd\u03b1\u03bd\u03c4\u03b9 56,1% \u03bc\u03b5 VRd \u03ba\u03b1\u03b9 lenalidomide, \u03bc\u03b5 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03ba\u03b1\u03c4\u03ac 65% \u03c4\u03bf\u03c5 \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03bf\u03cd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03ae \u03b8\u03b1\u03bd\u03ac\u03c4\u03bf\u03c5. \u0397 \u0398\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03b5 \u03b2\u03b1\u03c3\u03b9\u03ba\u03cc\u03c2 \u03c0\u03c5\u03bb\u03ce\u03bd\u03b1\u03c2 \u03c4\u03b7\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7\u03c2 PERSEUS, \u03c0\u03c1\u03bf\u03c3\u03ad\u03c6\u03b5\u03c1\u03b5 \u03c0\u03c1\u03ce\u03b9\u03bc\u03b7 \u03c0\u03c1\u03cc\u03c3\u03b2\u03b1\u03c3\u03b7 \u03c3\u03c4\u03b7\u03bd \u03ba\u03b1\u03b9\u03bd\u03bf\u03c4\u03cc\u03bc\u03bf \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c5\u03c0\u03bf\u03b2\u03bb\u03ae\u03b8\u03b7\u03ba\u03b5 \u03c3\u03b5 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03bc\u03b5 \u03b5\u03c0\u03b9\u03c4\u03c5\u03c7\u03af\u03b1 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u0391\u03bc\u03b5\u03c1\u03b9\u03ba\u03b1\u03bd\u03b9\u03ba\u03cc \u039f\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc \u03a4\u03c1\u03bf\u03c6\u03af\u03bc\u03c9\u03bd \u03ba\u03b1\u03b9 \u03a6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd \u03c4\u03c9\u03bd \u0397\u03a0\u0391 (FDA).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u03a0\u03b1\u03c1\u03ac\u03bb\u03bb\u03b7\u03bb\u03b1, \u03c4\u03b1 \u03c0\u03b5\u03bd\u03c4\u03b1\u03b5\u03c4\u03ae \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c4\u03b7\u03c2 CARTITUDE-2 \u03b1\u03bd\u03ad\u03b4\u03b5\u03b9\u03be\u03b1\u03bd \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03c4\u03b7\u03c2 CAR-T \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2 cilta-cel \u03cc\u03c4\u03b1\u03bd \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03c0\u03c1\u03c9\u03b9\u03bc\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ad\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2. \u03a3\u03c4\u03b1 \u03c0\u03ad\u03bd\u03c4\u03b5 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1, 54,2% \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03c0\u03b1\u03c1\u03ad\u03bc\u03b5\u03bd\u03b1\u03bd \u03c7\u03c9\u03c1\u03af\u03c2 \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03ba\u03b1\u03b9 69,2% \u03b5\u03bd \u03b6\u03c9\u03ae, \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03b5\u03bd\u03b9\u03c3\u03c7\u03cd\u03bf\u03c5\u03bd \u03c4\u03bf \u03b5\u03bd\u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03bf\u03bd \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03c0\u03c1\u03c9\u03b9\u03bc\u03cc\u03c4\u03b5\u03c1\u03b7 \u03b1\u03be\u03b9\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03c4\u03c9\u03bd CAR-T \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03b9\u03ce\u03bd.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u039c\u03af\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b9\u03c2 \u03c0\u03bb\u03ad\u03bf\u03bd \u03ba\u03b1\u03b9\u03bd\u03bf\u03c4\u03cc\u03bc\u03b5\u03c2 \u03b5\u03be\u03b5\u03bb\u03af\u03be\u03b5\u03b9\u03c2 \u03c4\u03bf\u03c5 \u03c3\u03c5\u03bd\u03b5\u03b4\u03c1\u03af\u03bf\u03c5 \u03ae\u03c4\u03b1\u03bd \u03bf\u03b9 \u03b1\u03bd\u03b1\u03ba\u03bf\u03b9\u03bd\u03ce\u03c3\u03b5\u03b9\u03c2 \u03b3\u03b9\u03b1 in vivo CAR-T, \u03b4\u03b7\u03bb\u03b1\u03b4\u03ae \u03c4\u03b5\u03c7\u03bd\u03bf\u03bb\u03bf\u03b3\u03af\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03b5\u03c0\u03b9\u03c7\u03b5\u03b9\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b4\u03b7\u03bc\u03b9\u03bf\u03c5\u03c1\u03b3\u03ae\u03c3\u03bf\u03c5\u03bd \u03c4\u03b1 CAR-T \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u03b1\u03c0\u03b5\u03c5\u03b8\u03b5\u03af\u03b1\u03c2 \u03bc\u03ad\u03c3\u03b1 \u03c3\u03c4\u03bf\u03bd \u03bf\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc \u03c4\u03bf\u03c5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03bf\u03cd\u03c2. \u03a0\u03b1\u03c1\u03bf\u03c5\u03c3\u03b9\u03ac\u03c3\u03c4\u03b7\u03ba\u03b1\u03bd \u03c0\u03c1\u03ce\u03b9\u03bc\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03b1\u03c0\u03cc \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03bb\u03b1\u03c4\u03c6\u03cc\u03c1\u03bc\u03b5\u03c2, \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03c9\u03bd \u03bf\u03c0\u03bf\u03af\u03c9\u03bd \u03c0\u03c1\u03bf\u03c3\u03b5\u03b3\u03b3\u03af\u03c3\u03b5\u03b9\u03c2 \u03ad\u03bd\u03b1\u03bd\u03c4\u03b9 BCMA \u03ae\/\u03ba\u03b1\u03b9 CD19. \u0391\u03bd \u03ba\u03b1\u03b9 \u03b7 \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1 \u03b2\u03c1\u03af\u03c3\u03ba\u03b5\u03c4\u03b1\u03b9 \u03b1\u03ba\u03cc\u03bc\u03b7 \u03c3\u03b5 \u03b1\u03c1\u03c7\u03b9\u03ba\u03cc \u03c3\u03c4\u03ac\u03b4\u03b9\u03bf, \u03b7 \u03b4\u03c5\u03bd\u03b1\u03c4\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae\u03c2 CAR-T \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd in vivo \u03b8\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03c3\u03b5 \u03bc\u03b5\u03bb\u03bb\u03bf\u03bd\u03c4\u03b9\u03ba\u03ac \u03bd\u03b1 \u03b1\u03c0\u03bb\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7\u03bd \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ae \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1, \u03c0\u03b1\u03c1\u03b1\u03ba\u03ac\u03bc\u03c0\u03c4\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c0\u03bf\u03bb\u03cd\u03c0\u03bb\u03bf\u03ba\u03b1 \u03c3\u03c4\u03ac\u03b4\u03b9\u03b1 \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7\u03c2 \u03b5\u03be\u03c9\u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03b4\u03b9\u03b5\u03c5\u03c1\u03cd\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03b4\u03c5\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7\u03bd \u03c0\u03c1\u03cc\u03c3\u03b2\u03b1\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u03a3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03ae\u03c4\u03b1\u03bd \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03c6\u03ac\u03c3\u03b7\u03c2 3 \u03c4\u03b7\u03c2 iberdomide, EXCALIBER-RRMM, \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03c5\u03c0\u03bf\u03c4\u03c1\u03bf\u03c0\u03b9\u03ac\u03b6\u03bf\u03bd \u03ae \u03b1\u03bd\u03b8\u03b5\u03ba\u03c4\u03b9\u03ba\u03cc \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03bf\u03cd\u03bd \u03bc\u03c5\u03ad\u03bb\u03c9\u03bc\u03b1. \u039f \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc\u03c2 iberdomide, daratumumab \u03ba\u03b1\u03b9 dexamethasone (IberDd) \u03c0\u03ad\u03c4\u03c5\u03c7\u03b5 MRD-\u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae \u03c0\u03bb\u03ae\u03c1\u03b7 \u03b1\u03bd\u03c4\u03b1\u03c0\u03cc\u03ba\u03c1\u03b9\u03c3\u03b7 \u03c3\u03c4\u03bf 41% \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03ad\u03bd\u03b1\u03bd\u03c4\u03b9 21% \u03bc\u03b5 daratumumab, bortezomib \u03ba\u03b1\u03b9 dexamethasone (DVd). \u03a4\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03b1\u03c5\u03c4\u03ac \u03bf\u03b4\u03ae\u03b3\u03b7\u03c3\u03b1\u03bd \u03c3\u03b5 \u03b5\u03c0\u03b9\u03c4\u03b1\u03c7\u03c5\u03bd\u03cc\u03bc\u03b5\u03bd\u03b7 \u03ad\u03b3\u03ba\u03c1\u03b9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03bf\u03cd \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd FDA \u03c4\u03c9\u03bd \u0397\u03a0\u0391. \u03a4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03b4\u03b7\u03bc\u03bf\u03c3\u03b9\u03b5\u03cd\u03b8\u03b7\u03ba\u03b1\u03bd \u03c4\u03b1\u03c5\u03c4\u03cc\u03c7\u03c1\u03bf\u03bd\u03b1 \u03c3\u03c4\u03bf \u03ad\u03b3\u03ba\u03c1\u03b9\u03c4\u03bf \u03b5\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03bf\u03bd\u03b9\u03ba\u03cc \u03c0\u03b5\u03c1\u03b9\u03bf\u03b4\u03b9\u03ba\u03cc Lancet Oncology<\/span><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u039f \u039a\u03b1\u03b8\u03b7\u03b3\u03b7\u03c4\u03ae\u03c2 \u0398\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae\u03c2 \u2013 \u0391\u03b9\u03bc\u03b1\u03c4\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2 <\/span><b>\u0395\u03c5\u03ac\u03b3\u03b3\u03b5\u03bb\u03bf\u03c2 \u03a4\u03ad\u03c1\u03c0\u03bf\u03c2<\/b><span style=\"font-weight: 400;\"> \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03b5\u03af\u03c7\u03b5 \u03c3\u03c4\u03b7\u03bd \u03ba\u03b5\u03bd\u03c4\u03c1\u03b9\u03ba\u03ae \u03b1\u03bd\u03c4\u03b9\u03c0\u03b1\u03c1\u03ac\u03b8\u03b5\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c3\u03c5\u03bd\u03b5\u03b4\u03c1\u03af\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b8\u03ad\u03c3\u03b7 \u03c4\u03c9\u03bd CAR-T \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd, \u03c4\u03c9\u03bd T-cell engagers \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd antibody-drug conjugates (ADC), \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03b9\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c4\u03b7 \u03b8\u03ad\u03c3\u03b7 \u03c4\u03c9\u03bd ADC. \u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1\u03c3\u03b5 \u03c4\u03b1 \u03c4\u03b5\u03bb\u03b9\u03ba\u03ac \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7\u03c2 \u03c6\u03ac\u03c3\u03b7\u03c2 2 \u03c4\u03b7\u03c2 \u0395\u03bb\u03bb\u03b7\u03bd\u03b9\u03ba\u03ae\u03c2 \u039f\u03bc\u03ac\u03b4\u03b1\u03c2 \u039c\u03b5\u03bb\u03ad\u03c4\u03b7\u03c2 \u03c4\u03bf\u03c5 \u039c\u03c5\u03b5\u03bb\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b5\u03b9\u03c3\u03b1\u03b3\u03c9\u03b3\u03b9\u03ba\u03ae \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03bc\u03b5 isatuximab, bortezomib, cyclophosphamide \u03ba\u03b1\u03b9 dexamethasone (IsaVCd), \u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03bf\u03cd\u03bc\u03b5\u03bd\u03b7 \u03b1\u03c0\u03cc \u03c3\u03c5\u03bd\u03c4\u03ae\u03c1\u03b7\u03c3\u03b7 \u03bc\u03b5 isatuximab \u03ba\u03b1\u03b9 lenalidomide, \u03c3\u03b5 \u03bd\u03b5\u03bf\u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03b8\u03ad\u03bd\u03c4\u03b5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u039f \u039a\u03b1\u03b8\u03b7\u03b3\u03b7\u03c4\u03ae\u03c2 \u0398\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae\u03c2 \u2013 \u03a0\u03b1\u03b8\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2 \u2013 \u039f\u03b3\u03ba\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2 <\/span><b>\u0395\u03c5\u03c3\u03c4\u03ac\u03b8\u03b9\u03bf\u03c2 \u039a\u03b1\u03c3\u03c4\u03c1\u03af\u03c4\u03b7\u03c2<\/b><span style=\"font-weight: 400;\"> \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03b5\u03af\u03c7\u03b5 \u03c3\u03c4\u03b7 \u03c3\u03c5\u03bd\u03b5\u03b4\u03c1\u03af\u03b1 \u201cMeet the Experts\u201d \u03bc\u03b5 \u03b8\u03ad\u03bc\u03b1 \u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u03bb\u03bf\u03b3\u03ae \u03c4\u03b7\u03c2 \u03b2\u03ad\u03bb\u03c4\u03b9\u03c3\u03c4\u03b7\u03c2 \u03b1\u03c0\u03b5\u03b9\u03ba\u03bf\u03bd\u03b9\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7\u03c2 \u03c3\u03c4\u03bf \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03bf\u03cd\u03bd \u03bc\u03c5\u03ad\u03bb\u03c9\u03bc\u03b1, \u03ad\u03bd\u03b1 \u03c0\u03b5\u03b4\u03af\u03bf \u03c0\u03bf\u03c5 \u03b1\u03c0\u03bf\u03ba\u03c4\u03ac \u03b1\u03ba\u03cc\u03bc\u03b7 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1 \u03ba\u03b1\u03b8\u03ce\u03c2 \u03b7 \u03b1\u03ba\u03c1\u03b9\u03b2\u03ae\u03c2 \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03b5\u03bd\u03c3\u03c9\u03bc\u03b1\u03c4\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c0\u03bb\u03ad\u03bf\u03bd \u03c4\u03cc\u03c3\u03bf \u03c3\u03c4\u03b9\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b1\u03c0\u03bf\u03c6\u03ac\u03c3\u03b5\u03b9\u03c2 \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03c3\u03c5\u03b6\u03ae\u03c4\u03b7\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03c4\u03bf\u03bd \u03bf\u03c1\u03b9\u03c3\u03bc\u03cc \u03c4\u03b7\u03c2 \u03af\u03b1\u03c3\u03b7\u03c2.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u0397 \u039a\u03b1\u03b8\u03b7\u03b3\u03ae\u03c4\u03c1\u03b9\u03b1 \u0398\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae\u03c2 \u2013 \u039f\u03b3\u03ba\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2 \u039c\u03b1\u03c1\u03af\u03b1 \u0393\u03b1\u03b2\u03c1\u03b9\u03b1\u03c4\u03bf\u03c0\u03bf\u03cd\u03bb\u03bf\u03c5 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03b5\u03af\u03c7\u03b5 \u03c3\u03b5 \u03b5\u03b9\u03b4\u03b9\u03ba\u03cc \u03b5\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03bf\u03bd\u03b9\u03ba\u03cc \u03c3\u03c5\u03bc\u03c0\u03cc\u03c3\u03b9\u03bf \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03b9\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c4\u03b9\u03c2 \u03c3\u03cd\u03b3\u03c7\u03c1\u03bf\u03bd\u03b5\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c3\u03c4\u03c1\u03b1\u03c4\u03b7\u03b3\u03b9\u03ba\u03ad\u03c2 \u03c0\u03c1\u03ce\u03c4\u03b7\u03c2 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03c0\u03bf\u03c1\u03b5\u03af\u03b1 \u03c0\u03c1\u03bf\u03c2 \u03c4\u03b7\u03bd \u03b5\u03c0\u03af\u03c4\u03b5\u03c5\u03be\u03b7 \u03bc\u03b1\u03ba\u03c1\u03bf\u03c7\u03c1\u03cc\u03bd\u03b9\u03bf\u03c5 \u03b5\u03bb\u03ad\u03b3\u03c7\u03bf\u03c5 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03b4\u03c5\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7\u03c2 \u03af\u03b1\u03c3\u03b7\u03c2. \u03a0\u03b1\u03c1\u03ac\u03bb\u03bb\u03b7\u03bb\u03b1, \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03b5\u03af\u03c7\u03b5 \u03c3\u03b5 \u03b5\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03bf\u03bd\u03b9\u03ba\u03cc \u03c3\u03c5\u03bc\u03c0\u03cc\u03c3\u03b9\u03bf \u03c3\u03c7\u03bf\u03bb\u03b9\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c4\u03b1 \u03c0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7\u03c2 EXCALIBER-RRMM \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03b8\u03ad\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03bf\u03cd \u03c4\u03b7\u03c2 iberdomide \u03bc\u03b5 daratumumab, dexamethasone \u03c3\u03c4\u03bf \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc \u03b1\u03bb\u03b3\u03cc\u03c1\u03b9\u03b8\u03bc\u03bf.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u03a4\u03ad\u03bb\u03bf\u03c2, \u03b7 \u0392\u03b9\u03bf\u03bb\u03cc\u03b3\u03bf\u03c2 <\/span><b>\u03a4\u03af\u03bd\u03b1 Bagratuni<\/b><span style=\"font-weight: 400;\"> \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1\u03c3\u03b5 \u03c0\u03c1\u03c9\u03c4\u03bf\u03b3\u03b5\u03bd\u03ae \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03c4\u03b7\u03c2 \u0398\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae\u03c2 \u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae\u03c2 \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ac \u03bc\u03b5 \u03c4\u03b7 \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1 \u03c4\u03c9\u03bd \u03ba\u03c5\u03ba\u03bb\u03bf\u03c6\u03bf\u03c1\u03bf\u03cd\u03bd\u03c4\u03c9\u03bd \u03ba\u03b1\u03c1\u03ba\u03b9\u03bd\u03b9\u03ba\u03ce\u03bd \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5 \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03bf\u03cd \u03bc\u03b5\u03c4\u03b1\u03bb\u03bb\u03b1\u03b3\u03bc\u03ad\u03bd\u03bf\u03c5 MYD88 \u03c3\u03c4\u03bf \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1 \u03c9\u03c2 \u03c0\u03c1\u03bf\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ce\u03bd \u03b2\u03b9\u03bf\u03b4\u03b5\u03b9\u03ba\u03c4\u03ce\u03bd \u03c3\u03c4\u03b7 \u03bc\u03b1\u03ba\u03c1\u03bf\u03c3\u03c6\u03b1\u03b9\u03c1\u03b9\u03bd\u03b1\u03b9\u03bc\u03af\u03b1 Waldenstr\u00f6m, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b1 \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ac \u03ba\u03b1\u03b9 \u03b3\u03bf\u03bd\u03b9\u03b4\u03b9\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03c0\u03bf\u03c5 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03b1\u03c3\u03b7 \u03c3\u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03bc\u03b5 ibrutinib.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u039f\u03b9 \u03b1\u03bd\u03b1\u03ba\u03bf\u03b9\u03bd\u03ce\u03c3\u03b5\u03b9\u03c2 \u03c4\u03bf\u03c5 IMS 2026 \u03ba\u03b1\u03c4\u03b1\u03b4\u03b5\u03b9\u03ba\u03bd\u03cd\u03bf\u03c5\u03bd \u03cc\u03c4\u03b9 \u03c4\u03bf \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc \u03c4\u03bf\u03c0\u03af\u03bf \u03c4\u03bf\u03c5 \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03bf\u03cd \u03bc\u03c5\u03b5\u03bb\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b5\u03be\u03b5\u03bb\u03af\u03c3\u03c3\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b5\u03be\u03b1\u03b9\u03c1\u03b5\u03c4\u03b9\u03ba\u03ac \u03b3\u03c1\u03ae\u03b3\u03bf\u03c1\u03bf\u03c5\u03c2 \u03c1\u03c5\u03b8\u03bc\u03bf\u03cd\u03c2. \u0397 \u03b5\u03c0\u03af\u03c4\u03b5\u03c5\u03be\u03b7 \u03b2\u03b1\u03b8\u03cd\u03c4\u03b5\u03c1\u03c9\u03bd \u03ba\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03bf \u03c0\u03b1\u03c1\u03b1\u03c4\u03b5\u03c4\u03b1\u03bc\u03ad\u03bd\u03c9\u03bd \u03b1\u03bd\u03c4\u03b1\u03c0\u03bf\u03ba\u03c1\u03af\u03c3\u03b5\u03c9\u03bd, \u03b7 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ce\u03bd \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03b9\u03ce\u03bd \u03c3\u03b5 \u03c0\u03c1\u03c9\u03b9\u03bc\u03cc\u03c4\u03b5\u03c1\u03b1 \u03c3\u03c4\u03ac\u03b4\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5, \u03b7 \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03bd\u03ad\u03c9\u03bd \u03b1\u03bd\u03bf\u03c3\u03bf\u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03b9\u03ce\u03bd \u03ba\u03b1\u03b9 \u03b7 \u03c0\u03c1\u03bf\u03bf\u03c0\u03c4\u03b9\u03ba\u03ae \u03bd\u03b5\u03cc\u03c4\u03b5\u03c1\u03c9\u03bd \u03bc\u03bf\u03c1\u03c6\u03ce\u03bd \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ae\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2 \u03b4\u03b7\u03bc\u03b9\u03bf\u03c5\u03c1\u03b3\u03bf\u03cd\u03bd \u03c0\u03bb\u03ad\u03bf\u03bd \u03c4\u03b9\u03c2 \u03c0\u03c1\u03bf\u03cb\u03c0\u03bf\u03b8\u03ad\u03c3\u03b5\u03b9\u03c2 \u03ce\u03c3\u03c4\u03b5 \u03b7 \u03b5\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03c3\u03c5\u03b6\u03ae\u03c4\u03b7\u03c3\u03b7 \u03bd\u03b1 \u03bc\u03b5\u03c4\u03b1\u03ba\u03b9\u03bd\u03b5\u03af\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b1\u03b4\u03b9\u03b1\u03ba\u03ac \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03ac\u03c4\u03b1\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b5\u03c0\u03b9\u03b2\u03af\u03c9\u03c3\u03b7\u03c2 \u03c0\u03c1\u03bf\u03c2 \u03c4\u03b7 \u03bc\u03b1\u03ba\u03c1\u03bf\u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03cd\u03c6\u03b5\u03c3\u03b7 \u03c7\u03c9\u03c1\u03af\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03ba\u03b1\u03b9, \u03b3\u03b9\u03b1 \u03ad\u03bd\u03b1 \u03bc\u03ad\u03c1\u03bf\u03c2 \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd, \u03c0\u03c1\u03bf\u03c2 \u03c4\u03b7\u03bd \u03c0\u03c1\u03bf\u03bf\u03c0\u03c4\u03b9\u03ba\u03ae \u03c4\u03b7\u03c2 \u03af\u03b1\u03c3\u03b7\u03c2.<\/span><\/p>\n<\/p><\/div>\n\n<br \/><a href=\"https:\/\/www.zougla.gr\/ygeia\/pa8isis-prolipsi\/neoteres-exelixeis-sti-therapeia-tou-pollaplou-myelomatos\/\" class=\"google-drive-opener\">\u0394\u03b7\u03bc\u03bf\u03c3\u03b9\u03b5\u03cd\u03c4\u03b7\u03ba\u03b5 !  <\/a> 2026-10-05 10:31:00<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u03a3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ad\u03c2 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content=\"\u039d\u03b5\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03b5\u03be\u03b5\u03bb\u03af\u03be\u03b5\u03b9\u03c2 \u03c3\u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c4\u03bf\u03c5 \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03bf\u03cd \u03bc\u03c5\u03b5\u03bb\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 - eportal\" \/>\n\t\t<meta name=\"twitter:description\" content=\"\u03a3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03bb\u03af\u03be\u03b5\u03b9\u03c2 \u03c3\u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c4\u03bf\u03c5 \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03bf\u03cd \u03bc\u03c5\u03b5\u03bb\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03b9\u03ac\u03c3\u03c4\u03b7\u03ba\u03b1\u03bd \u03c3\u03c4\u03bf 23\u03bf \u0395\u03c4\u03ae\u03c3\u03b9\u03bf \u03a3\u03c5\u03bd\u03ad\u03b4\u03c1\u03b9\u03bf \u03c4\u03b7\u03c2 International Myeloma Society (IMS), \u03c0\u03bf\u03c5 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